The end of aging: how close the science really is, and what breaks if it works

Twelve biological hallmarks like senescent cells drive decay and act like bad apples in a barrel.

Metformin and rapamycin show promise for extending healthspan by targeting the cellular general contractor protein.

Epigenetic reprogramming can restore youthful gene expression in mice without deleting the cell's operating system.

The current three-stage life model fails when retirement lasts fifty years instead of fifteen.

Scientific progress risks stalling because new ideas often advance only when older leaders pass away.

Compressed morbidity aims for people to live vibrantly until one hundred then go out like a light.